MBP full form in medical term is Myelin Basic Protein that is found in the myelin sheath. This is the protective covering that surrounds nerve fibers in the central and peripheral nervous systems.
The myelin sheath is important for the proper functioning of nerve cells, and MBP plays a critical role in maintaining the stability and structure of the myelin sheath.
MBP is a highly conserved protein found in many species, including humans. It is programmed by the MBP gene, placed on chromosome 18 in humans. The MBP protein is produced by cells called oligodendrocytes & Schwann cells.
Besides its role in maintaining the structure of the myelin sheath, MBP has also been shown to have other functions. For instance, it may play a role in cell signaling and gene regulation. It has been implicated in neurological and psychiatric disorders, including multiple sclerosis, schizophrenia, and bipolar disorder.
MBP can be used as a biomarker to monitor disease activity and progression in multiple sclerosis. Different levels of MBP in the cerebrospinal fluid have been associated with increased disease activity and severity in multiple sclerosis.